Corneal elasticity in cross-linking using Brillouin microscopy, published in IOVS
We studied depth-resolved corneal elasticity after cross-linking treatment using Brillouin Microscopy. The anterior stroma contributes the most to the stiffening of the cornea following cross-linking. The standard epi-on cross-linking is 3 times more efficient in stiffening the cornea than the epi-off procedure. The study is the result of a collaboration between Yun’s Lab at Wellman Center of Photomedicine (Harvard-MGH) and the Visual Optics and Biophtonics Lab, Institute of Optics, CSIC.
Full reference: Giuliano Scarcelli, Sabine Kling, Elena Quijano, Roberto Pineda, Susana Marcos, and Seok Hyun Yun Brillouin Microscopy of Collagen Crosslinking: Noncontact Depth-Dependent Analysis of Corneal Elastic Modulus, Investigative Ophthalmology and Vision Science 54:1418-1425 (2013)