Cross-linking (CXL) treatment aims at stiffening the cornea of keratoconic patients, with weakened corneas.

Dibujo

Cross-linking (CXL) treatment aims at stiffening the cornea of keratoconic patients, with weakened corneas.
The study investigates corneal deformation imaging and inherent corneal mechanical properties in ex vivo rabbit eyes following conventional CXL (using Riboflavin as a photosensitizer and UVA light, UVX) and a novel CXL modality (using Rose Bengal and green light, RGX). While corneal deformation is less, the treated area is more stiffened in treated corneas. The lower penetration and lack of dehydration in RGX are advantageous in the new CXL modality.
This study is part of collaborative work between VioBio Lab (IO-CSIC) and Kochevar Lab (Wellman Center of Photomedicine)
The work is published in the current issue of Investigative Ophthalmology and Vision Science.

Full reference: N. Bekesi, I Kochevar, S. Marcos Corneal Biomechanical Response Following Collagen Cross-Linking With Rose Bengal–Green Light and Riboflavin-UVA. Investigative Ophthalmology & Visual Science March 2016, Vol.57, 992-1001

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Posted on April 4, 2016, in General. Bookmark the permalink. Leave a comment.

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