Material Properties from Air Puff Corneal Deformation in model and porcine corneas, published in PLOS One
Fig. 1.Model cornea (MC). A. Model cornea made out of hydrophilic contact lens material. B. Model cornea mounted in artificial eye chamber.
Fig. 6. FE model of the model eye with the applied boundary conditions.
Fig 10. Stress-strain curves of the MC materials and porcine corneas by the inverse modeling from air-puff measurements and from uniaxial extensiometry measurements. C: Material Q
We used model polymer corneas of different materials and thicknesses and porcine corneas ex vivo (at constant intraocular pressure) to validate an inverse optimization approach to retrieve material properties from air puff corneal deformation imaging. Material properties were compared with those obtained from uniaxial extensiometry revealing high similarity. In polymer artificial corneas material properties were retrieved independent on corneal thickness. The study demonstrates that the combination of air puff corneal deformation imaging with inverse modeling is a reliable non-invasive technique to estimate corneal mechanical properties. The study has just been published in PLOSOne.
Full reference: Bekesi N, Dorronsoro C, de la Hoz A, Marcos S (2016) Material Properties from Air Puff Corneal Deformation by Numerical Simulations on Model Corneas. PLoS ONE 11(10): e0165669. doi:10.1371/journal.pone.0165669
Link to publication.
Link to CSIC Press Release