Susana Marcos discusses ERC Advanced Grant in Fundación Madri+d Notiweb

Sin título

The Fundación Madrid+d Science and Technology News interviewed Susana Marcos on the research undertaken under ERC Advanced Presbyopia, her experience on the ERC programs and recommendations to potential applicants.

Read full interview here



Mengchan Sun’s PhD Public Defense: “Biometric Measurements in the Crystalline Lens: Applications in Cataract Surgery”


Mengchan Sun will defend her thesis “Biometric Measurements in the Crystalline Lens: Applications in Cataract Surgery” next September 12 (12:00h) at Salón de Grados, Facultad de Medicina, Universidad de Valladolid.

Rehearsal: September 11th (12:00h), at Sala de Juntas, Instituto de Óptica, CSIC.

Susana Marcos discusses VioBio Lab research and technology activities in various press interviews


In a series of interviews in Spanish Media, Prof. Susana Marcos, Director of the Visual Optics and Biophotonics Lab discusses the research work on vision, diagnostics and improvement carried at in the lab, as well as its technological and clinical impact.

Interview in Voz Pópuli, “Entrevista a Susana Marcos” by Antonio Martínez Ron:

Interview in La Gaceta de Salamanca: “Un jurado con 18 Premios Nobel corona a la salmantina Susana Marcos”:

Interview in Salud Digital, “En España, la fotónica y la óptica visual tienen un prestigio superior al de muchos países”:

More press releases here:

Rose Bengal Corneal Cross-linking : Clinical and Histological changes published in IOVS


Following studies on the corneal biomechanical changes induced by Rose Bengal CXL in vivo in an experimental model on rabbits, we report on the histology and clinical observations in the cornea in a 60-day follow up, in comparison with contralateral eyes left after control (de-epithealized). It was found that cell death was restricted to the anterior central stroma, and the cellular decrease did not differ significantly between RGX and DE corneas. Cell proliferation in the epithelium and stroma appeared at 2 days. In both DE and RGX corneas, recovery of the epithelium was complete at day 30, although cell repopulation of the stroma was not complete at 60 days. Rose Bengal CXL appears therefore an efficient and safe method to increase corneal stiffness, with significant advantages over traditional UV Cross-linking (use of visible light, less penetration and much faster application). The work is the result of a collaboration between Wellman Center of Photomedicine, MGH-Harvard Medical School (Irene Kochevar’s Lab), Universidad de Valladolid (Carmen Martinez’s Lab) and Instituto de Optica CSIC (VioBio Lab).

Full reference: Patricia Gallego-Muñoz; Lucía Ibares-Frías; Elvira Lorenzo; Susana Marcos; Pablo Peréz-Merino; Nandor Bekesi; Irene E. Kochevar; M. Carmen Martínez-García. Corneal Wound Repair After Rose Bengal and Green Light Crosslinking: Clinical and Histologic Study. Investigative Ophthalmology & Visual Science July 2017, Vol.58, 3471-3480.

Full article:

Temporal multiplexing by SimVis, new publication in Biomedical Optics Express

getImage (1)

The SimVis technology to simulate multifocal corrections relies on fast tunable lenses (temporal multiplexing). We propose a method to generate and evaluate the temporal profile describing real multifocal lenses (segmented refractive, trifocal diffractive and extended depth of focus) based on the fitting of the through-focus (TF) optical quality of the multifocal component of a given multifocal lens to a linear combination of TF optical quality of monofocal lenses viable with a tunable lens. Visual Strehl ratio and TF simulated images obtained with estimated time coefficients closely matched those predicted with the M-IOL. The study also investigates the effects of temporal sampling, varying pupil size, monochromatic aberrations, longitudinal chromatic aberrations and temporal dynamics on SimVis.

Full reference: Vyas Akondi, Carlos Dorronsoro, Enrique Gambra, and Susana Marcos. “Temporal multiplexing to simulate multifocal intraocular lenses: theoretical considerations,” Biomed. Opt. Express 8, 3410-3425 (2017) 

Full article:

Susana Marcos awarded Premio Rey Jaime I in “New Technologies”

Premios Jaime I


The jury of Premios Rey Jaime I, one of the most prestigious awards in Spain, announced the winners of the 2017 edition in a formal event at the Palau de la Generalitat Valenciana. Susana Marcos has received the Premio Rey Jaime I in “New Technologies” for her “important contributions to the field of the physics of vision and, in particular, her studies on imaging and ocular diagnostics that had led to the development of new intraocular lenses and the detection of ocular diseases.”

More information:


New in the lab: Sara El Aissati and Ana María Gonzalez-Ramos

Sin título

We welcome Sara El Aissati and Ana María Gonzalez-Ramos to VioBio Lab. Sara El Aissati has a degree in Optometry (2015) and a Masters in Optical Technologies by Universidad Complutense de Madrid.  Ana María Gonzalez-Ramos holds a BSc in Optometry (2015) and a MSc in Optical Technologies by Universidad Complutense de Madrid.  They are joining the VioBio Lab under the Comunidad de Madrid Youth Guarantee Program and will be working in the fields of adaptive optics visual simulations and characterization of the optical quality of the eye with contact and intraocular lenses.

More information about  Youth Guarantee Program in the following links:


New in the lab: Elena Rico


We welcome Elena Rico in VioBio Lab, joining as Project Assistant. Elena holds a BSc in Biology by Universidad Autónoma de Madrid and a MSc in Biotechnology by Aliter International Business School. Elena worked as project assistant in the European Project IS IT GREEN (Lifelong Learning Programme) and in the Madrid Biotechnology Companies Association (BioMadrid), where she gained experience in management and institutional relations.  

VioBio Lab offers two CSIC JAE Intro Fellowships in Visual Optics and Biophotonics



CSIC has launched the JAE Intro Program, a 2-month fellowship program for Master students to gain experience in research environments.

VioBio Lab (Instituto de Óptica) will host 2 of the 100 offered fellowships, to work on Adaptive Optics Visual Simulations and High Resolution Imaging in the eye. Candidates need to have a degree in Physics, Engineering and/or Optics, a competitive CV (>7/10 average score), and a motivation to enroll in a dynamic multidisciplinary research program. Deadline for applications is May 9. The expected starting date is Sept-Oct 2017.

Reference code for the fellowships are:



Full information on the program can be found in:
Documents in English include the Summary of the call and FAQ

Interested candidates can apply directly through CSIC webpage. We recommend that candidates communicate motivation/intention by emailing


Evaluation of the True Wavefront Aberrations in Eyes Implanted With a Rotationally Asymmetric Multifocal Intraocular Lens published in Journal of Refractive Surgery


Is it possible to separate the wavefront aberrations of the eye from the multifocal intraocular lens pupillary power distribution after a cataract surgery? Our recent paper answers this question using OCT and LRT measurements in the case of a commercially available rotationally asymmetric segmented refractive multifocal intraocular lens, Lentis Mplus (Oculentis GmbH, Berlin, Germany). Custom analysis of ray tracing–based retinal spot diagrams allowed decoupling of the true higher order aberrations of the patient’s eye from the power pupillary distribution of the Lentis Mplus IOL, therefore providing the appropriate phase map to accurately evaluate through-focus optical quality. The method was tested using ray tracing optical simulations in a computer eye model virtually implanted with the Lentis Mplus IOL, with a generic cornea or with anterior segment geometry obtained from custom quantitative spectral-domain optical coherence tomography in a real patient. The method was applied to laser ray tracing aberrometry data at near and far fixation obtained in a patient implanted with the Lentis Mplus IOL.

Full reference: Akondi V, Pérez-Merino P, Martinez-Enriquez E, Dorronsoro C, Alejandre N, Jiménez-Alfaro I, Marcos S. Evaluation of the True Wavefront Aberrations in Eyes Implanted With a Rotationally Asymmetric Multifocal Intraocular Lens. J Refract Surg. 2017; 33(4): 257-265. doi: 10.3928/1081597X-20161206-03

Full article:

%d bloggers like this: