Monthly Archives: October 2019

Pre-operative simulation of post-operative multifocal vision published in Biomedical Optics Express


While multifocal intraocular lenses are increasingly implanted to correct for presbyopia, how one sees with a multifocal correction is hard to explain and imagine. The current study evaluates the quality of various visual simulating technologies by comparing vision with simulated MIOLs pre-operatively and the implanted MIOLs post-operatively in the same patients. Two simulation platforms were used: a custom-developed Adaptive Optics system, with two visual simulator devices: a spatial light modulator (SLM) and an optotunable lens operating under temporal multiplexing (SimVis); and the wearable, binocular, large field of view clinical simulator SimVis Gekko developed by CSIC spin-off company 2Eyes Vision. All devices were programmed to simulate a trifocal diffractive MIOL (POD F, FineVision, PhysIOL). Through-focus decimal visual acuity was measured in eight patients pre-operatively simulating the trifocal lens and post-operatively with implantation of the same MIOL. The article published in Biomedical Optics Express shows that visual simulations are useful programmable tools to predict visual performance with MIOLs, both in an Adaptive Optics environment and in a clinical simulators, since pre-operative visual simulations and post-operative data are in good agreement.

Full reference: Maria Vinas, Sara Aissati, Mercedes Romero, Clara Benedi-Garcia, Nuria Garzon, Francisco Poyales, Carlos Dorronsoro, and Susana Marcos, “Pre-operative simulation of post-operative multifocal vision,” Biomed. Opt. Express 10, 5801-5817 (2019).

Full article here

Susana Marcos received Ramón y Cajal Medal at the Spanish Royal Academy of Science

Medalla RyC

Ramón y Cajal Medal Award Ceremony took place at the Spanish Royal Academy of Science on October 23rd in an event presided by the President of the Academy D. Jesús María Sanz, Secretary of State Ángeles Heras and CSIC President Rosa Menéndez. 

The Ramón y Cajal Medal highlights the work of Spanish scientists under 50. The jury of the award pointed that Prof. Marcos has maintained an outstanding scientific career at an international level, with a fully multidisciplinary research program to understand the basic mechanisms of human vision, develop diagnostic tools in ophthalmology and to invent new optical solutions for the correction of the most common vision problems. 

More information: Real Academia de Ciencias Exactas, Físicas y Naturales

Monovision and the Misperception of Motion published in Current Biology


Monovision is a common prescription lens correction for presbyopia. Each eye is corrected for a different distance, causing one image to be blurrier than the other. Millions of people have monovision corrections, but little is known about how interocular blur differences affect motion perception. In a paper published in Current Biology, we report that blur differences cause a motion illusion that makes people dramatically misperceive the distance and three-dimensional direction of moving objects. The effect occurs because the blurry and sharp images are processed at different speeds. For moving objects, the mismatch in processing speed causes a neural disparity, which results in the misperceptions. The results show that these misperceptions can be severe enough to impact public safety and demonstrate that they can be eliminated with novel combinations of non-invasive ophthalmic interventions. The motion illusion and the paradigm we use to measure it should help reveal how optical and image properties impact temporal processing, an important but understudied issue in vision and visual neuroscience.

Full reference: Johannes Burge, Victor Rodriguez-Lopez, Carlos Dorronsoro. “Monovision and the Misperception of Motion”, Current Biology 29, 1–7 (2019)

Full article here

Presenting LightLens, a CaixaImpulse project


CaixaImpulse presents the LightLens project, a tech transfer venture of an accommodating intraocular lens developed by the Visual Optics and Biophotonics Lab. The concept, prototype and demonstration of an intraocular lens capable of dynamically reshape is the result of the European Research Council Advanced Grant PRESBYOPIA. This new project promotes its next steps into commercialization.

Watch the video presenting the CaixaImpulse project here

More information about the project here


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