OCT-based model of the guinea pig eye in vivo published in Biomedical Optics Express


A full 3-D eye model based on quantitative optical coherence tomography is presented for guinea pigs of two ages in vivo (awake and under cycloplegia). Biometric parameters obtained from OCT included cornea and lens surface elevations and radii of curvature, interocular distances, crystalline lens volume, diameter, equatorial lens position and surface area. There was a good correspondence (except for spherical aberration, likely due to the presence of GRIN) between the ocular aberrations measured with laser ray tracing and predicted from the eye model.

The study is published in Biomedical Optics Express, as part of the special issue “25 Year Anniversary of OCT”.

Full reference: Pablo Pérez-Merino, Miriam Velasco-Ocana, Eduardo Martinez-Enriquez, Luis Revuelta, Sally A McFadden, and Susana Marcos. “Three-dimensional OCT based guinea pig eye model: relating morphology and optics” Biomed. Opt. Express 8, 2173-2184 (2017).

Full article: https://www.osapublishing.org/boe/abstract.cfm?uri=boe-8-4-2173

Susana Marcos appointed to the Scientifc Advisory Board of the Spanish Agency of Research (AEI)


The Agencia Estatal de Investigación has appointed Prof. Susana Marcos to its Scientific Advisory Board. The board is formed by a group of 12 prestigious scientists. Other scientists from CSIC included in the board are Avelino Corma, Angela Nieto, Alberto Enciso and Carme Torras.

The AEI is the Spanish research funding agency. Recently launched with a new management model, it aims at improving planning of funding of research activities.


Vision Research publishes Question-Answer format Paper on the State of the Field of Adaptive Optics

vision-researchA new paper published in the Special Issue in Vision Research on Adaptive Optics includes a revision of the technology and its applications in Vision Science, including visual psychophysics, visual simulation, retinal imaging, ocular biology and neurophysiology. The article is structured in a Question and Answer format from leaders in the field (the authors of the paper), led by the special issue guest editors Stephen A. Burns, John S. Werner and Susana Marcos.

The article is in press in Vision Research: Marcos et al.  Vision science and adaptive optics, the state of the field.  


Fundación Madri+d Notiweb features CSIC spin-off company 2Eyes Vision


Álvaro Sánchez-Lozano, Business Developer in the SimVis project, explains the development of 2Eyes Vision, a spin-off company of the Visual Optics and Biophotonics Lab (Institute of Optics, CSIC, Madrid). You can learn about SimVis, a technology to simulate corrections for presbyopia, in an interview by Fundación Madrid+d.

More information on 2Eyes Vision at http:://www.2eyesvision.com

Susana Marcos’ interview in SECPHO News


Susana Marcos discusses the latest research in VioBio Lab and her views on science and technology transfer in this interview in SECPHO News. SECPHO is the Southern European Cluster in Photonics and Optics.

You can read the full interview in this link: http://www.secpho.org/wp-content/uploads/2017/01/Susana-Marcos_Enero2017vdef.pdf

New in the lab in a joint position with Wellman Center of Photomedicine (MGH, Harvard): Dr.Judith Birkenfeld


We welcome back Judith Birkenfeld in VioBio Lab. She is joining through a Marie Curie COFUND Fellowship (Fundacion Madri+d) jointly Wellman Center (Andy Yun’s Lab) and the Institute of Optics, CSIC (VIOBIO Lab) . Judith’s background is in Physics (MSc, Heidelberg University) and Visual Optics and Biophotonics (PhD Universidad Complutense de Madrid), having graduated under the supervision of Prof. Susana Marcos. She joins back after M+Vision Postdoctoral Fellowship work at MIT, Brigham Women Hospital and Mass General Hospital working on translational projects in biomedicine. Her interests are in the area of ocular imaging (OCT and microscopy) and applications to ocular biomechanics.

OCT- based full crystalline lens shape as a function of accommodation in vivo, published in Biomedical Optics Express


A newly developed method to estimate the entire lens shape based on 3-D quantitative imaging is applied to the evaluation of the lens changes in volume, surface area, equatorial position and equatorial lens diameter, in young eyes in vivo. The study is the first assessment of the full accommodating crystalline lens in vivo using high resolution optical imaging.

The work has been published in Biomedical Optics Express as part of a Special Issue on Optical Coherence Tomography Full reference:

Eduardo Martinez-Enriquez, Pablo Pérez-Merino, Miriam Velasco-Ocana, and Susana Marcos, “OCT-based full crystalline lens shape change during accommodation in vivo,” Biomed. Opt. Express 8, 918-933 (2017)


2-year Postdoctoral Advanced Fellowship in Biophotonics @VioBio_Lab



The Visual Optics and Biophotonics Lab seeks candidates for a 2-year COFUND Postdoctoral Application in Biophotonics to develop projects of excellence/innovation in the area of ocular imaging, ocular biomechanics and/or vision correction

The Multiply COFUND Program

The Multiply COFUND Fellowship is partially funded by the European Commission (H2020 Marie Sklodowska Curie Program) and VIOBIO Laboratory Funds.

• Salary: 53,000-55,000 €/year (including Social Security obligations).

The successful applicant will work on development and applications of imaging techniques in the anterior segment of the eye, ocular biomechanics or adaptive optics. Applications range from understanding the basic ocular mechanisms to the evaluation and new designs of alternatives for vision correction.

Full description of Fellowship Program:  http://multiply.astonphotonics.uk/

Fellowship Starting date: November 2017

Eligible Candidates

Eligible candidates are international or Spanish citizens that have not resided in Spain for more than one year in the previous three years.

Must hold a PhD degree and an excellent background.

Experience in Biomedical Imaging (Ocular imaging preferred) with strong motivation for multidisciplinary research in the field of ophthalmic and ocular biology applications

 Must be fluent in English.

The Visual Optics and Biophotonics Lab

The Visual Optics and Biophotonics Lab, led by Prof. Susana Marcos, provides a young and dynamic research environment. The laboratory is funded primarily by European grants (ERC Advanced Grant), national programs and holds excellent collaborative programs with top international laboratories, clinical institutes and industry. The Lab is part of t EU MyFun Marie Curie ITN Research of Excellence, MIT M+Vision Consortium, among others. The Institute of Optics (CSIC) is the oldest research institute in Optics in Spain, and holds an excellent reputation of research in optics, particularly in Visual Optics. CSIC (www.csic.es) is the National Center for Research in Spain, and the most important multidisciplinary research facility in the country, and among the highest ranked in Europe.

Full information regarding VIOBIO Lab activities: http://www.vision.csic.es

Application Process

Applicants should send Expressions of Interest to the VIOBIO Lab Project Managment Unit at: viobio@io.cfmac.csic.es before February 15, 2017 and should include CV, research interests and names of three references.

Pre-selected candidate(s) will proceed with the full application procedure, which requires a cover letter, CV, a research proposal (in collaboration with host institution VioBio Lab), Letter of Commitment from host institution, scan of photo ID, scan of PhD certificate and residence certificate (last 3 years). Letters of Recommendations will be requested at this stage.

Formal applications will be made through a dedicated website.

Final application deadline: March 31, 2017.

What has VioBio published in 2016?

foto revista 2.png

We have compiled a slide show presenting the peer review publications by VioBio Lab in 2016.  Topics include corneal biomechanics, crystalline lens, wavefront sensing and visual simulations of multifocal corrections for presbyopia, and journals include IOVS, Biomedical Optics Express, Optica, PLOS One, Journal of Cataract and Refractive Surgery, Applied Optics and Journal of Refractive Surgery.

Please, visit this link to learn more on what came out from VioBio in 2016.

SimVis technology featured in Ophthalmology Business

The Ophthalmology Business Review has featured the article “Portable device simulates different IOLs before surgery” which describes SimVis, a portable see-through visual simulator of multifocal corrections. The system is based
in the concept of temporal multiplexing (Dorronsoro et al. Optica 2016) and its current version is binocular and wearable. SimVis is developed by 2Eyes Vision, a spin-off company of VioBio Lab-CSIC
A link to the article can be found here
Link to 2 Eyes Vision website.

%d bloggers like this: