Author Archives: vioBioLab

Prof. Susana Marcos awarded Premio Nacional de Investigación 2019


The acting Minister of Science, Innovation and Universities, Pedro Duque, announced the winners of the 2019 National Research Awards and congratulated them on behalf of the Government. The jury agreed to award Prof. Susana Marcos with the National Research Award ‘Leonardo Torres Quevedo’ in the area of Engineering for its pioneering contributions to optical and photonic engineering, and to the industrial development of diagnostic and correction instruments in ophthalmology which have benefited thousands of patients.

The National Research Awards represent the most important recognition in the field of scientific research in Spain. They aim to distinguish the merit of those researchers of Spanish nationality who have outstanding work in scientific fields of international relevance and who contribute exceptionally to the advancement of science, the transfer of technology and the progress of humanity.

More information:


Off-axis OCT imaging of the crystalline lens to reconstruct the GRIN using optical methods published in Biomedical Optics Express


We demonstrate that both the gradient refractive index (GRIN) of the crystalline lens and the posterior surface shape can be studied using on an off axis OCT images. We had proposed in the past the use of OCT images to reconstruct the crystalline lens GRIN but our method needed accurate measurements of the anterior and posterior surface of the lens. This is impossible in vivo because the image of the posterior surface of the lens is distorted by the optics of the eye (including the unknown lens GRIN!). In this new study we show that using information from both on- and off-axis OCT images, the four GRIN variables and the posterior surface shape can be studied simultaneously. The current study shows results in 9 isolated crystalline lenses. Using isolated lenses allow us to check that the reconstructions of the GRIN and the posterior surface shapes are accurate. However, the ideas can be directly applied in vivo where yes, there are a few more complications such as the refraction of the rays in the corneal surface.

Full reference: Alberto de Castro, Judith Birkenfeld, Bianca Maceo Heilman, Marco Ruggeri, Esdras Arrieta, Jean-Marie Parel, Fabrice Manns, and Susana Marcos, “Off-axis optical coherence tomography imaging of the crystalline lens to reconstruct the gradient refractive index using optical methods” Biomed. Opt. Express 10 (7), 3622-3634 (2019)

Full article here

Job offer: Four-year postdoctoral contract

Captura IO

The Visual Optics and Biophotonics Lab (Institute of Optics, CSIC) is seeking candidates (PhD in Physics or Engineering) interested in a 4-year postdoctoral position to develop a project in the field of Visual Optics and Engineering in the eye, offering an exciting opportunity to join a highly internationally recognized laboratory which develops R&D focused on optical engineering, photonics and biomechanics.

See full profile and contact details here.

VioBio Lab Project selected for Fundación Madri+d HealthStart Program


Fundación Madri+d HealthStart, a program aimed at promoting commercialization and spin-out of highly added value research results, has awarded one of its 2019 Projects to our Light-engaged accommodating Intraocular Lens. The program kicks off June 27 with a training, pitching and networking event. Congratulations! 

VioBio Lab in Science TV Show Orbita Laika


Orbita Laika, the popular science television show broadcast on Radio Television Española – La2, showed the research of the Visual Optics and Biophotonics Lab (Institute of Optics, CSIC). Clara Benedí, predoctoral researcher at VioBio Lab, explained current work on Optical Coherence Tomography, intraocular implants and visual simulators.

  • Link to the interview here 
  • Orbita Laika show here



VioBio Lab at ARVO 2019 (Vancouver, Canada)


You can now check VioBio Lab contributions to ARVO 2019 Annual Meeting on adaptive optics, visual simulation, crystalline lens morphology, corneal biomechanics, accommodating IOLs and cross-linking, and include them in your ARVO itinerary.

Sunday April 28

08:00-09:45. Poster Session. James Germann. Depth-resolved collagen order after in vivo rabbit corneal cross-linking

13:00-14:45. Poster Session:
Susana Marcos “Crystalline lens Gradient Index Profile in the guinea pig myopia model”
Sara Aissati “Testing the effect of ocular aberrations on perceived Transverse Chromatic Aberration”
Shrilekha Vedhkrishnan “Adaptive-optics vision simulation of multifocal lenses for myopia progression”

Monday April 29

11:15-13:00. Poster Session. Geethika Muralidharan “Crystalline lens accommodation through multifocal corrections”

Tuesday April 30

8.45-10:30. Poster Session. Andres de la Hoz. “Photobonded silk-fibroin films for corneal dressing”.

11:45-13:30. Poster Session:
Eduardo Martinez-Enriquez “Eigenlenses: an eigenvectors-based model for full crystalline lens shape description”
Clara Benedi-Garcia “Perceived best focus and visual performance upon induction of astigmatism in presbyopes”

Wednesday May 1

8:30-8:45. Paper Session. Victor Rodriguez-Lopez “Direct subjective refraction with temporal defocus waves”

Thursday May 2

10:15-12:00. Poster Session. Judith Birkenfeld “Assessment of asymmetries in biomechanical properties from corneal deformation imaging”

10:15-10:30. Paper Session. Alberto de Castro “Intra-Ocular Lens Power Calculation using 3D OCT-based Personalized Computer Eye Models”

10:45-11:00. Paper Session. Carlos Dorronsoro “Perceptual and physical limits to temporal multiplexing simulation of multifocal corrections”

11:30-11:45. Paper Session. Maria Vinas “Optical and visual quality with physical and visually simulated presbyopic multifocal contact lenses”

11:45-12:00. Paper Session. Xoana Barcala “Perceptual differences across binocular corrections for presbyopia”

For more information check the ARVO online planner.

Prof. Susana Marcos awarded Ramon y Cajal Medal by the Royal Academy of Sciences

Medalla Ramon y Cajal

The Royal Academy of Sciences, gathered in extraordinary plenary session on March 27, agreed to award the Ramón y Cajal Medal 2019, which rewards the trajectory of Spanish scientists under 50, to Prof. Susana Marcos. 

The jury of the award pointed that Prof. Marcos “has maintained an outstanding scientific career at an international level, with a fully multidisciplinary research program, using concepts of physics, optics, biology, biomechanics, ophthalmology and neuroscience to understand the basic mechanisms of human vision, develop diagnostic tools in ophthalmology and to invent new optical solutions for the correction of the most common vision problems. His work, highly productive both in the academic field and in technology transfer, has a high impact on basic science, the clinic and the ophthalmic industry”.

More information: Real Academia de Ciencias


New in the Lab: Elena Campillo


We welcome Elena Campillo (BSc in Physics, Universidad Complutense de Madrid) who joined Viobio lab with a Predoctoral Fellowship of YEI Program funded by Comunidad de Madrid. She performed her degree practises at IMDEA Nanoscience working at Hypertermia (cancer research with nanoparticles) continuing her final Bachelor Thesis at Instituto de Magnetismo Aplicado.

Elena holds a MSc in Biomedical Technologies Management and Development from the Universidad Carlos III de Madrid. She did her master thesis at Centro de Investigaciones Energéticas, Medioambientales y Tecnológicas (CIEMAT).

She will work on Perception and Psychophysics using optotunable lenses.

SILK-EYE, a new ERC Advanced Grant announced to VIOBIO Lab

Silkeye collage I

The European Research Council has announced this year’s ERC Advanced Grant projects, SILK-EYE led by Professor Susana Marcos (Visual Optics and Biophotonics Lab, Institute of Optics, CSIC, Spain) being one of the 10 new grantees from Spanish research institutions. This new ERC grant, follows ERC AdG PRESBYOPIA, ERC PoC OCT4IOL, ERC PoC SimVisSim and ERC PoC LightAIOL, previously granted to the group.

SILKEYE will develop a unique set of strategies for the generation of ocular implants based on silk biomaterials that are more biocompatible and versatile than current synthetic implants, and safer, more functional, more accessible and more affordable than allografts. The project will produce high impact results at the interface of photonics and biology, and has the potential to revolutionize how major corrective procedures in ophthalmology are performed.

Pablo Sanz Diez, MyFun ITN Marie Curie Fellow, secondment at VioBio Lab


We welcome Pablo Sanz Diez to VioBio Lab as a visiting Fellow of the Marie Curie MyFun ITN. Pablo holds a Bachelor in Optics and Optometry and a MSc in Advanced Optic and Optometric Techniques from the University of Murcia, and a MSc in Clinical Optometry and Vision from University of Alicante. He is currently a Marie Curie Early Career Fellow at Carl Zeiss Vision, Tuebingen, and he is visiting VioBio Lab for 3 weeks to undertake studies relating the effect of stimulus features with crystalline lens shape and accommodation.

More information about the MyFUN Innovative Training Network  here.


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