Estimation of scleral mechanical properties from air-puff OCT, published in Biomedical Optics Express

Scleral biomechanics play an important role in the progression of myopia (near-sightedness), but it is challenging to measure it non-invasively. In our recent publication we introduce air-puff deformation imaging as a method to estimate the biomechanical properties of the sclera of an intact eye globe. The sclera was excited via an air-pulse at several globe locations, and the deformation was imaged using optical coherence tomography (OCT). The maximum apex deformation, the deformation velocity, and the arc-length during deformation was investigated. The elastic modulus of the sclera was then estimated using an inverse optimization technique based on finite element modeling. 

Full reference: David Bronte-Ciriza, Judith S. Birkenfeld, Andrés de la Hoz, Andrea Curatolo, James A. Germann, Lupe Villegas, Alejandra Varea, Eduardo Martínez-Enríquez, and Susana Marcos, “Estimation of scleral mechanical properties from air-puff optical coherence tomography,” Biomed. Opt. Express 12, 6341-6359 (2021)

Link to the article here