IMCUSTOMEYE landmark paper on first multi-meridian corneal imaging device to measure a promising early keratoconus biomarker published in Biomedical Optics Express

An EU Horizon 2020 IMCUSTOMEYE project landmark paper has just been published in Biomedical Optics Express. It is the result of a collaboration between CSIC, University of Liverpool, and the Polish Academy of Science. It presents the first multi-meridian corneal imaging device, based on a swept-source optical coherence tomography system with high transverse scanning frame rates, to measure a promising early keratoconus biomarker based on air-puff-induced deformation asymmetry. The system will serve both as the basis for determining the minimum viable specifications for a keratoconus screening device based on a deformation asymmetry biomarker, and as a platform to estimate patient-specific corneal biomechanical properties, that can be fed in corneal surgery planning simulators. Currently the system is employed in a pilot clinical study with Keratoconus and Lasik-candidate subjects in collaboration with Fernandez Vega Ophthalmological Institute.

Full reference: Andrea Curatolo, Judith S. Birkenfeld, Eduardo Martinez-Enriquez, James A. Germann, Geethika Muralidharan, Jesús Palací, Daniel Pascual, Ashkan Eliasy, Ahmed Abass, Jędrzej Solarski, Karol Karnowski, Maciej Wojtkowski, Ahmed Elsheikh, and Susana Marcos, “Multi-meridian corneal imaging of air-puff induced deformation for improved detection of biomechanical abnormalities,” Biomed. Opt. Express 11, 6337-6355 (2020)

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Contact lenses, the reverse Pulfrich effect, and anti‑Pulfrich monovision corrections published in Scientific Reports

The reverse Pulfrich effect is an optical illusion that causes misperceptions of laterally moving objects caused by interocular blur differences, like those produced by monovision, a common correction for presbyopia. Here we demonstrate that (1) contact lenses and trial lenses induce indistinguishable reverse Pulfrich effects, (2) anti-Pulfrich corrections are equally effective when induced by contact and trial lenses, and (3) magnification differences do not cause or impact the Pulfrich effect. 

The study is the result of collaborative work between the Visual Optics and Biophotonics Lab (Institute of Optics, CSIC) and Johannes Burge (Department of Psychology, University of Pennsylvania). 

Full reference: Victor Rodriguez-Lopez, Carlos Dorronsoro, Johannes Burge. Contact lenses, the reverse Pulfrich effect, and anti‑Pulfrich monovision corrections. Scientific Reports, 10, 16086 (2020). 

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